WebJan 6, 2014 · Histiocytic proliferative disorders are commonly observed in dogs and less often cats. Histiocytic disorders occur in most of the dendritic cell (DC) lineages. Canine cutaneous histiocytoma originates from Langerhans cells (LCs) indicated by expression of CD1a, CD11c/CD18, and E-cadherin. When histiocytomas occur as multiple lesions in … WebFeb 23, 2013 · To date, only 30 cases of Langerhans cell sarcoma, including the present case, have been reported. We report a new case of Langerhans cell sarcoma that presented with multifocal cutaneous involvement. Diagnosis was done based on histopathological, immunohistochemical evaluation, as well as ultrastructural analysis …
Diagnosis and Discussion -- Case 1058 - UPMC
WebDec 3, 2024 · Skin dendritic cells, including Langerhans cells express c-MET, which when activated induces emigration of Langerhans cells from skin [60,61]. Thus, a similar program to MET-driven EMT (epithelial–mesenchymal transition) is mediated in Langerhans cells upon inflammatory activation, indicating an important role of HGF/c … WebLangerhans cell sarcoma (LCS) is rare and aggressive; patients have an overall survival rate of less than 50%. We present a 62-year-old man with a history of superficial spreading melanoma of the upper back with sentinel lymph node metastasis, Langerhans cell histiocytosis, and LCS. The patient pres … refrigeration mushrooms dunk
Successful treatment of an elderly Langerhans cell sarcoma …
WebJul 1, 2024 · Langerhans cell sarcoma (LCS) is a rare malignant neoplasm of the Langerhans cells characterized by multiorgan involvement and an aggressive clinical course. 1 LCS is identified histopathologically by the presence of cytologically malignant histiocytoid cells with longitudinally grooved nuclei, prominent nucleoli, and a … WebAll 4 patients with Langerhans cell sarcoma (100%) and 6 of 22 pediatric (age < 18 years) patients with Langerhans cell histiocytosis (27.3%) had positive results for IGF2BP3; however, 16 of 22 ... WebFeb 23, 2013 · Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells with notably malignant cytological features. Reports of LCS are sparsely available in English literature; to the ... refrigeration monitoring icon