Cytoplasmic protein nck2

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August undefined, 2024

WebSep 26, 2024 · cytoplasmic protein NCK2, NCK adaptor protein 2, SH2/SH3 adaptor protein NCK-beta, growth factor receptor-bound protein 4 GeneRIFs: Gene References Into Functions Authors propose that Nck2 should be further investigated as a regulator of the reliance of white adipose tissue on hyperplasia versus hypertrophy during adipose … WebNck2 is an adaptor protein composed of 3N-SH3 domains followed by a unique Cterminal SH2 domain. It interacts with PINCH in integrin signal transduction, cell migratio and …

Depletion of the Adaptor Protein NCK Increases UV …

WebThis gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function … WebNX_O43639 - NCK2 - Cytoplasmic protein NCK2 - Sequence. Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular … razzy bailey rockin\u0027 in the parking lot

Entry - *604930 - NCK ADAPTOR PROTEIN 2; NCK2 - OMIM

WebAdapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. This gene encodes a member of the NCK family of … WebCytoplasmic protein NCK2 (also known as NCK-beta and Grb4) is a protein that in humans is encoded by the NCK2 gene. Contents. 1 Function; 2 Interactions; ... Fan JS, Song J (Jun 2006). "Structural insight into the binding diversity between the human Nck2 SH3 domains and proline-rich proteins". Biochemistry. 45 (23): 7171–84. doi:10.1021 ... WebAug 19, 2014 · Most cells also express Nck2 (NCK adapter protein 2, NP_001004720.1) a structural and functional paralog with 68% sequence identity to Nck1, and Grb2 (CAG46740.1), which is similar except that it has only two SH3 domains. ... Nck1 is a cytoplasmic protein. (A) 50 µg of each of nuclear and cytoplasmic extract was … sims 2 clothes maternity

NCK2 antibody I01/7A10 - bio-rad-antibodies.com

NCK2 NCK adaptor protein 2 [ Homo sapiens (human) ]

NCK belongs to family of adaptor proteins. There are two mammalian NCK genes, NCK1 and NCK2. NCK1 is located in chromosome 3 and NCK2 is located in chromosome 2. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to … See more Cytoplasmic protein NCK2 (also known as NCK-beta and Grb4) is a protein that in humans is encoded by the NCK2 gene. See more NCK2 has been shown to interact with: • Epidermal growth factor receptor, • LIMS1, • PDGFRB, See more • Nck2 Info with links in the Cell Migration Gateway Archived 2014-12-11 at the Wayback Machine See more • Li W, Hu P, Skolnik EY, Ullrich A, Schlessinger J (Dec 1992). "The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors" See more WebNCK2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 403 amino acids (1-380) and having a molecular mass of 45.3kDa. … razzy fresh pittsburghWebRecombinant Human Nck-2 protein is an Escherichia coli Full length protein 1 to 380 aa range, > 85% purity and validated in SDS-PAGE, MS. ... Cytoplasmic protein NCK2; GRB4; Growth factor receptor bound protein 4; NCK adaptor protein 2; Nck-2; NCK2; NCK2_HUMAN; NCKbeta; razzyroo headbands

"WebTarget Information. The NCK family of SH2/SH3 adaptor proteins consists of two members, NCK1 and NCK2, which couple tyrosine kinase signaling, including the EGF and PDGF receptor-pathways, to downstream signaling proteins. The NCK2 protein binds human PDGFR-b (Tyr-1009); overexpression of NCK2 inhibits PDGF-induced membrane … " - Cytoplasmic protein nck2

Cytoplasmic protein nck2

NCK2 protein expression summary - The Human Protein …

WebThis gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function … WebDescription: Homo sapiens NCK adaptor protein 2 (NCK2), transcript variant 1, mRNA. (from RefSeq NM_003581) RefSeq Summary (NM_003581): This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind …

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WebNck-2 is a ubiquitously expressed adaptor protein comprising primarily three N-terminal SH3 domains and one C-terminal SH2 domain. We report here that Nck-2 interacts with … Web31 rows · May 10, 2002 · Function. Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or ...

WebAnti-NCK2 antibodies are offered by a number of suppliers. This target gene encodes the protein 'NCK adaptor protein 2' in humans and may also be known as GRB4, NCKbeta, cytoplasmic protein NCK2, and SH2/SH3 adaptor protein NCK-beta. Structurally, the protein is reported to be 42.9 kilodaltons in mass. WebDec 8, 2024 · 393972 - Gene Resultnck2a NCK adaptor protein 2a [ (zebrafish)] Predicted to enable receptor tyrosine kinase binding activity and signaling adaptor activity. …

WebNov 28, 2015 · Adaptor protein sorting nexin 17 interacts with the scavenger receptor FEEL-1stabilin-1 and modulates its expression on the cell surface ... AP-2, adaptor protein-2; APC, antigen- presenting cells; CMV, cytomegalovirus; CT, cytoplasmic tail; DiI, 1:1′-dioctadecyl- 3:3:3′:3′-tetramethyl-indocarbo-cyanine perchlorate; DMEM, Dulbecco´s ... WebPrimePCR™ Template for Probe Assay: Nck2, Rat Reaction: 4 billion copies/200 µl Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay. List Price: $215.00 Your Price: Log In Quantity: Add to Cart [ Add to My PrimePCR ] ...

WebDescription: Homo sapiens NCK adaptor protein 2 (NCK2), transcript variant 2, mRNA. (from RefSeq NM_001004720) RefSeq Summary (NM_001004720): This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown …

WebMouse anti NCK2 antibody recognizes cytoplasmic protein NCK2, also known as GRB4. NCK2, alongside NCK1, comprise the NCK family of SH2/SH3-containing adaptor proteins. These proteins couple activated membrane receptors to specific downstream effectors, with a range of biological effects. sims 2 clothing sets razzy bailey i keep coming backWebUse Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed. sims 2 clothing store shelf ccWebFeb 2, 2009 · Nck interacts with an extended proline-rich stretch within the cytoplasmic part of the FasL via its second and ... Suzuki K, Yamada M, Kojima M, Hatanaka H, Koizumi S: Brain-derived neurotrophic factor promotes interaction of the Nck2 adaptor protein with the TrkB tyrosine kinase receptor. Biochem Biophys Res Commun. 2002, 294: 1087-1092. … sims 2 clothing sets ccWebG-protein-coupled receptor kinase-interacting protein 1 (GIT1) is enriched in both presynaptic and postsynaptic terminals and after phosphorylation is targeted to the synapse by binding to cytoplasmic protein GRB4 (NCK2 aka GRB4).GRB4 binds by its SH2 domain to Tyr392 (Human Tyr383) in the synaptic localization domain (SLD) of GIT1. sims 2 clothes dumpWebThe .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. razz youth and enjoymentWebMar 3, 2008 · Cowan and Henkemeyer (2001) demonstrated that the SH2/SH3 domain adaptor protein GRB4 (NCK2) binds to the cytoplasmic domain of B ephrins (e.g., 300035) in a phosphotyrosine-dependent manner. In response to B-ephrin reverse signaling, cells increase FAK ( 600758 ) catalytic activity, redistribute paxillin ( 602505 ), lose focal … sims 2 clothes teen