WebAcquista Anti-DRAK1 Anticorpo (A43116). Applicazioni Convalidate: WB. Reattività Testata: Human. ️ Alta qualità ️ Prezzi bassi ️ Garanzia al 100% Web28 ott 2024 · DRAK1 inhibits the growth and metastasis of advanced cervical cancer cells through two pathways: interfering with the homo-oligomerization of tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) and specifically reducing the stability of TRAF6 protein through an autophagy-mediated degradation pathway (Park et al., 2024).
Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase …
Web30 ott 1998 · The present study describes the cloning of two novel serine/threonine kinases termed DRAK1 and DRAK2, whose catalytic domains are related to that of death-associated protein kinase, a serine/threonine kinase involved in apoptosis. Both DRAKs are composed of the N-terminal catalytic domain and the C- … Web1 ott 2014 · DRAK1 specifically binds to Smad3 through its kinase domain, thereby blocking recruitment of Smad4 and translocation of Smad3 into nucleus. Thus, our findings suggest that aberrant expression of DRAK1 increases tumorigenic potential through the inhibition of TGF-β1 tumor suppressor activity in head and neck cancer cells. ottofond eck-badewanne modena corner
Rabbit anti-DRAK1 Antibody - Fortis Life Sciences
WebC Cell viability assay of DRAK1-knockdowned HeLa cells upon paclitaxel treatment ranging from 2.5 to 40 nM. The data represent the mean ± S.D. of three independent experiments. *p < 0.05; ... Web17 gen 2024 · 7QUE, 7QUF. PubMed Abstract: Serine/threonine kinase 17A (death-associated protein kinase-related apoptosis-inducing protein kinase 1─DRAK1) is a part … Web19 lug 2024 · Overexpression of DRAK1 triggers apoptosis in the absence of RNase L activation by activating c-Jun N-terminal kinase (JNK), translocation of BCL2 Associated X (Bax) to the mitochondria accompanied by cytochrome C release and loss of mitochondrial membrane potential promoting cleavage of caspase 3 and Poly(ADP-Ribose) … otto foods poughkeepsie